Microdosing is like picking up 5 IQ points and an antidepressant at the same time. 0.1g will do you for a start, then maybe increase to around 0.2 as you feel comfortable. It's much easier to manage the dose with LSD, though LSD has less of a stimulant effect.
Like anything else it's dose-dependent. You can have a couple beers and feel great, drink half a bottle of vodka and you're going to be miserable. That said, unlike the grand experience of puking your guts out after 15 margaritas, "miserable" on a heroic dose of psychedelics is just your ego losing the ability to suppress all the negative feelings and habits lurking in your subconscious, and absolutely freaking the fuck out about it. If you relax and "embrace the suck," you can realize you are not your ego and don't have to panic when it panics, and then you can objectively observe the crap things in your mind, and basically once they're in the sunlight they have no power. It's a hell of an experience but it's also like packing 10 years of elite level therapy into one night. I realized, for example, exactly why I have been so terrified of heights all my life, internalized it and I'm not scared of heights any more.
But you never have to do that if you don't want to. Microdosing is fine, just like having a beer is fine.