yes and no, in reality he had burned so many bridges over decades from his raging mental issues and insecurity that people just were sick of him on a personal level and wanted him gone and that was a good excuse.
on top of that, it was just so obvious that he wasn't really talented, he was just a "hard worker", the sad fact is that if you just get the coffee faithfully like a good work dog then often in show biz you get thrown a bone, and then if you surround your self with more talented people, you can hide the fact that you actually contribute nothing for years, but he wound up getting rid of all the people around him that were more talented, so it just became too blindingly obvious that he offered nothing to the people who paid him. the numbers don't lie and people were not at all listening to opie do radio by him self in the same numbers that they were when anthony was around or even when it was just opie and jim norton.
like it was one thing when he had the falling out with anthony, it was another thing when he also had a falling out with jim norton of all people. jim norton is like one of the friendliest, accomodating, non confrontational people you could ever meet, and not only did opie have a falling out with both of them, he fucking did it live on air to be forever immortalized, you can literally go listen to the shows where opie and anthony had their falling outs or when opie and jim did and you literally hear the moment when jim decides to quit and not come back to the show. and its literally all becasue of how blindingly insecure and self loathing opie is. its actually fascinating from a psychological stand point.
some people think that hard work will get you everywhere, but actually charisma does. when you work with someone full time, you often see them more then your own family, people will happily work with someone who is friendlier over someone who is a "hard worker"